In recent years, climate change has already become tangible for many people and regions. The historic decision of the World Climate Agreement of Paris defined the goal of limiting global temperature rise below 2 degrees. However, research has shown that even if climate-relevant emissions are reduced immediately, unavoidable consequences of climate change can be expected. In addition, Austria is particularly affected by climate change. With an almost twice as high temperature increase compared to the global average, it is becoming more and more important for us, in addition to climate protection, to adapt to existing and future climate change effects. The consequences of climate change show regional differences. These arise due to the small-scale structure and the topographically different conditions and their dependent characteristics of the climate as well as due to different socio-economic starting points in the respective regions. For a successful adaptation, therefore, in addition to the early and proactive planning, the region-specific design of the measures is crucial. In order to ensure a good adaptation, all (potential) measures have to be considered from the beginning and examined from different points of view in order to prevent a mismatch or the spatial displacement of damage. All these challenges are addressed by the present Climate Change Adaptation Model Regions program. The Climate Change Adaptation Model Regions program gives regions the opportunity to adapt professionally to climate change and implement activities in their communities to minimize potential damage and take advantage of the opportunities that arise.